Manual of PlantcircBase
Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) that are involved in transcriptional and posttranscriptional gene expression regulation. Typical circular RNA molecules comprise canonically spliced exonic sequences and are covalently closed. They have recently been shown to be expressed in eukaryotes (Salzman et al. 2012, Jeck et al. 2013, Memczak et al. 2013, Salzman et al. 2013), including plants (Wang et al. 2014, Ye et al. 2015, Lu et al. 2015).
In PlantcircBase (http://ibi.zju.edu.cn/plantcircbase/), we collected publicly available back-splice junction sequences and their full-length sequences of circRNAs identified in plants by us and other groups. Based on the collected circRNAs, we further predicted those circRNAs putatively acting as miRNA sponges and their potential networks involving circRNA-miRNA-mRNA in the corresponding species. In the database, you can find plant circRNAs and their related information, such as their sequences, host genes, expression, experimental validation as well as bioinformatics tools such as BLASTcirc (Zhang et al. 2017) for searching and visualizing circRNAs. Detail release information could be found here.