Bioinplant Lab

Bioinplant Lab of Zhejiang University

本实验室为浙江大学作物科学研究所、生物信息学研究所、IBM生物计算实验室、中美植物与医学健康联合研究中心重要组成部分。利用生物信息学和基因组等组学技术优势，我们主要开展（1）植物基因组及大数据育种技术；（2）组学大数据分析方法、数据库与工具；（3）植物比较医学与健康。具体包括作物及其野生植物基因组解析、基因组为导向的大数据育种技术、单细胞、三维基因组非编码RNA等生物信息学分析方法及其工具、基于组学数据的农产品制品安全评价、动植物肿瘤发生等保守遗传机制、植物跨界调控等研究。[简介] [全家福]

The Bioinplant lab is a part of Institute of Crop Sciences, Institute of Bioinformatics, IBM Biocomputing Laboratory and Sino-US Plant and Health Medicine Joint Reasearch Center, Zhejiang University. Our purpose is to further knowledge of genomes for crop breeding and complex traits/diseases, particularly through approaches of bioinformatics and omics. Our current research interests focus on (1) genomes of crops and their relatives and approaches to bridge the gap between genomics and crop improvement, such as genome-based breeding techniques; (2) Algorithms, databases, bioinformatic tools for omic data from single-cells, 3D genomes, etc.; (3) plant comparative medicine and health, such as comparative studies on diseases (tumors, scar, etc) in both plant and human, cross-talk of plant genetic elements (miRNA) in human, omic data-based approaches for safety evaluation of agricultural products.

最新消息（News）

Ø 浙江大学樊龙江团队建立植物单细胞RNA分析数据库（2021-05-06）

Ø 樊龙江教授应邀首届植物单细胞生物学国际研讨会上进行报告（2021-04-27）

Ø 樊龙江教授应邀华南农大-Molecular Plant作物科学前沿暨中衡山论坛进行报告（2021-04-25）

Ø 樊龙江教授受邀发表评述纪念Trends创刊25周年（2021-04-20）

Ø 樊龙江教授参与拍摄浙江大学英文形象片“Bigger Starts Here” （2021-04-08）

Ø 本实验室发表水稻生物信息学研究综述文章（2021-04-07）

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教学材料（Courses）

Ø 《生物信息学》（第二版），樊龙江主编，2021年5月底科学出版社发行

Ø 《植物基因组学》，樊龙江主编，2020；图片下载；重磅！《植物基因组学》出版；[韩斌院士序] ；[后记]

Ø 《生物信息学札记（第4版）》；《生物信息学》，樊龙江主编，2017；[郝柏林院士序言]

Ø 植物科学常用数据库和生物信息学工具（Mol Plant编辑部，2020）

Ø 《NGS时代的BSA百科全书》序言（樊龙江，2020）

Ø “生物信息学”（樊龙江，2002）（《破译生命密码——基因工程》，浙江大学出版社）

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数据库与生物信息学工具（Databases and Tools）

PlantscRNAdb: A Database for Plant Single-cell RNA Analysis

RiceRelativesGD: a database of rice relatives for rice research

PlantcircBase：a database for plant circular RNAs

BnPedigome: a genomic database for the pedigrees and breeding of Brassica napus

PcircRNA-finder：a program to identify circular RNAs in plants

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近期发表论文（Recent Publications）

PlantscRNAdb: A Database for Plant Single-cell RNA Analysis. Hongyu Chen, Xinxin Yin, Longbiao Guo, Jie Yao, Yuwen Ding, Xiaoxu Xu, Lu Liu, Zhu Qian-Hao, Qinjie Chu*, Longjiang Fan*. Molecular Plant, 2021. doi:https://doi.org/10.1016/j.molp.2021.05.002

Rice bioinformatics in the genomic era: status and perspectives. Lei Jia, Lingjuan Xie, Sangting Lao, Qian-Hao Zhu, Longjiang Fan*. The Crop Journal, 2021. doi:https://doi.org/10.1016/j.cj.2021.03.003

An ABCC-type transporter endowing glyphosate resistance in plants. Lang Pan, Qin Yu*, Junzhi Wang, Heping Han, Lingfeng Mao, Alex Nyporko, Anna Maguza, Longjiang Fan, Lianyang Bai*, Stephen Powles*. PNAS, 2021. doi:https://doi.org/10.1073/pnas.2100136118

De-domestication: an extension of crop evolution. Wu Dongya, Sangting Lao, Longjiang Fan*. Trends in Plant Science, 2021. doi:https://doi.org/10.1016/j.tplants.2021.02.003

Orphan crops and their wild relatives in the genomic era.（Perspective） Chu-Yu Ye, Longjiang Fan*. Molecular Plant, 2021. doi:https://doi.org/10.1016/j.molp.2020.12.013 [PDF][Featured Article][Cover story]

The genomes of the allohexaploid Echinochloa crus-galli and its progenitors provide insights into polyploidization-driven adaptation. Chu-Yu Ye, Dongya Wu, Lingfeng Mao, Lei Jia, Jie Qiu, Sangting Lao, Meihong Chen, Bowen Jiang, Wei Tang, Qiong Peng, Lang Pan, Lifeng Wang, Xiaoxiao Feng, Longbiao Guo, Chulong Zhang, Elizabeth Kellogg, Kenneth Olsen, Lianyang Bai, Longjiang Fan*. Molecular Plant, 2020. doi:https://doi.org/10.1016/j.molp.2020.07.001 [PDF] [MP Spotlight]