Plant Circular RNA Database

Detail information of BGIOSGA033849_circ_igg.1

			
						 General Information
					
						CircRNA Name
						BGIOSGA033849_circ_igg.1
					
						ID in PlantcircBase
						osi_circ_003181
					
						Alias
						11:16781729|16786282
					
						Organism
						
							Oryza sativa ssp. indica						
					
						Position
						
							chr11: 16781729-16786282  JBrowse»						
					
						Reference genome
						
							Oryza_indica.ASM465v1.42						
					
						Type  
						
							igg-circRNA							
									
						Identification method
						find_circ
					
						Parent gene
						
							NA						
					
						Parent gene annotation
						
							NA							
					
						Parent gene strand
						NA
					
						Alternative splicing
						
							BGIOSGA033849_circ_g.1 						
					
						Support reads
						NA
					
						Tissues
						leaf
					
						Exon boundary  
						
							NA-NA							"Exon boundary" shows whether the splicing sites are on the boundary of exons or not. For example, "Yes-No" represents the donor splicing site is on the exon boundary and the accepter is not on the exon boundary.

						Splicing signals  
						
							CT-AC							The splicing signals of the circRNA. For example, "AG-GT" represents that the donor and the accepter splicing signal is "AG" and "GT", respectively.

						Number of exons covered
						NA

General Information
CircRNA Name	BGIOSGA033849_circ_igg.1
ID in PlantcircBase	osi_circ_003181
Alias	11:16781729\|16786282
Organism	Oryza sativa ssp. indica
Position	chr11: 16781729-16786282 JBrowse»
Reference genome	Oryza_indica.ASM465v1.42
Type	igg-circRNA
Identification method	find_circ
Parent gene	NA
Parent gene annotation	NA
Parent gene strand	NA
Alternative splicing	BGIOSGA033849_circ_g.1
Support reads	NA
Tissues	leaf
Exon boundary	NA-NA "Exon boundary" shows whether the splicing sites are on the boundary of exons or not. For example, "Yes-No" represents the donor splicing site is on the exon boundary and the accepter is not on the exon boundary.
Splicing signals	CT-AC The splicing signals of the circRNA. For example, "AG-GT" represents that the donor and the accepter splicing signal is "AG" and "GT", respectively.
Number of exons covered	NA

			
						 Experimental Information
					
						Sanger sequencing for BSS  
						
							NA							Sanger sequencing for back-splicing site (BSS) validation. "Yes" represents Sanger sequencing has been performed to valid the back-splicing site, "No" represents the opposite, "NA" represents "not available".

						PCR primers for BSS   
						
							NA							PCR primers used in back-splicing site (BSS) validation.

						Sanger sequencing for FL   
						
							NA							Sanger sequencing for full-length (FL) sequence validation of circRNAs. "Yes" represents Sanger sequencing has been performed to valid the full-length of circRNA, "No" represents the opposite.

						PCR primers for FL   
						
							NA							 PCR primers used in full-length (FL) sequence validation.

Experimental Information
Sanger sequencing for BSS	NA Sanger sequencing for back-splicing site (BSS) validation. "Yes" represents Sanger sequencing has been performed to valid the back-splicing site, "No" represents the opposite, "NA" represents "not available".
PCR primers for BSS	NA PCR primers used in back-splicing site (BSS) validation.
Sanger sequencing for FL	NA Sanger sequencing for full-length (FL) sequence validation of circRNAs. "Yes" represents Sanger sequencing has been performed to valid the full-length of circRNA, "No" represents the opposite.
PCR primers for FL	NA PCR primers used in full-length (FL) sequence validation.

			
				
						 Sequences
					

				
						Splice junction sequence  
						
							TAAAGGCTAAGCACCTGTAGAGACCATGGACAGCAAGGTTCAATGCTTCTGTGTAAGCAGCTGG
ATTTTGCCGCAGAGATTGATCTCTGTCTATGTCAATctctgacctcttcgttcccagcttccca
aaaaacagaagatgtggagtatgcgacagctaaaccatgtgtttccaagagtatagcatagcaa
actccaac

									
								

					

						Assembled circRNA sequence  
						
							NA
The sequence of a circRNA based on assembly using circseq-cup (Ye et al., 2016) or CIRI-full (Zheng and Zhao, 2018) or CIRCexplorer2 (Zhang et al., 2016).

					

						Full-length trsnacripts
						
							NA						
					

						Genomic sequence
						
							CTCTGACCTCTTCGTTCCCAGCTTCCCAAAAAACAGAAGATGTGGAGTATGCGACAGCTAAACC
ATGTGTTTCCAAGAGTATAGCATAGCAAACTCCAACTTGAGGAACGGTCATTGGCCTCAAGGAT
CCTGACCCACTCAAATCTCAGAGCAGCCACTAGTCTGCAGAGTGACCTTGTCCCTTGCAGCCAG
GTCTTTTGCATAATAGGCACCAAACGACCTCCTAATCCCGCTAAAAGATAACGGATGGAATATG
TGGAGATCAAGCCTTTGGGATCAGCATTGTGACATACCCGTAACGCCAGACAGAAGCTCCACAC
GGTCTCTCTTTAGATCCTCATGTGAGCAGTGAGCTCTCCGGGATCATTGACAGCTCCAAAATCA
ACACTATTAATCGCGGCAGTTCCATCCGCATGAGGTAGTTTCATCAAACACGTTACGAAGGGCA
GGGCATGGGGGCATTCCGATGGCTTTCTGCAAAGTCCCTGACTATACGCTTAAGGGTTCTTCCG
CCTTTCCCTTGCATGTAAGCATGGTTGTTTCTGACATTATCACCAGTCCTACTGTGAAGATAGT
CTGAGGCTGCATCATGAAGTACGTTGAGCCATAAAGGAACTATCATCTCAGCTTCCCCTTGCCT
TAGGTACTCTGAGGGCATAGATTTCACCTGGACAAGATTGGAAAAACGTTAGCCCATGATGGTG
TTGCAACACGTCAAAGTTAAGCTTCATGCAGAAAATACATTAGTCGGAAATACTTTTCAAATGA
ATATAACACGCCAAAACACCAGAAGGTAGCTCAAAATGTTCAGGTGTCAACAGTACTTGTTACT
AGTCCGACATGACAACAATGTCTGCCTACAATCCTACATATATGGATTAATGGCTAGTATGTAG
ATGCAAACTGATGATTTCTAGTGACTAAAAATTAGTGTATCATGTAAATCAAATAAACAGAAAT
ATCATCTGTAATTTTCAAATGATATTTGACCCAGATCCTCTTGCAAATCCACGTCATGTTCATC
GTGATTTTCAAGATTGATGTACAGTACTACTAACCTTATGCATGACATGTGTTCTAATGCTTTG
ATGTTAGACGAACAAAAAAATAAACAAAAACACATAGGGTTCCTTTCGCAATTACACCAAGGGG
GTTATTGTAGAAATGCAGTACCGCTGATTGCAGCCATCGACAAAGGGAATCCCAAGAAATAATG
GCCTTCCACGTTGTTCTCTCACAGAGGCTGCACACTGCTGCCAACTGCTGCAATATTGTTGCAG
ATTTATGCACCTGTTGGAAAGAAAGAAATGTGAATATCATGCAAAGTCTCTATGGCCACATATC
CTGCCCTCTGAGTGGACCATATTTATAAAAGAATCAAATCATAGATATGATCAATGGTACTAAA
CTGGAAAAGCAACAGAAAGTAAACTTTAAGCAAGTAATCATTATGGTCAGGGTGCAAACATAAG
CGAGGGAAAAGGTAAAAAGATGGGCTTTGAAGCACAAGCATAGGAGCAATTGTGTGGAAGCAAT
GGTACGATGGTGCTCTTTGAAACTGTACCCACCCTTGACAAGGCCGATACACCAAGTAGAGCAT
AAAGTACATTTGACATGAGACCTTCACCGCAGCGTGCCAAAATTTGAGCTAGCACCACACCAGG
TGATCCATCAGAGGGGTGCTCTCGAGATTCTAGTGCAGCAGCGAGGCTAACATCAAGAAAACCT
ACATGTGTCATGGCAAATGATCAAATGAGCACAAAAACATACTAGGTGCTACACGATGTTTCAA
GTGCAATAGCTTGAGCTGAATGCTGAAGCATATGTCACAGTAACAGATTAAGGTATGTAAACGG
TATGAACAGTGCAGCAAGTACAAATAGATCTTTTAACTCCAAAGGGATTATAAATGTGATGAAA
AGAATAACGCTTTCTACCACCAACTCACATTACAGTGATACACTAGTTCCAACAGACATAATAA
TGTAACAAACCTTATCCAGAAAGTAGCTGAAAAGGCATCCATGACTTTGCAGGGGAAAAACACT
AACTTGACATGATTGCTTACCAGTAGACCACAATCCAAGCATTATTTTTCTTTGCATATACTTT
ATCTTCTCAGGGGAATAAATTTCTTTAAATTAAAAAACCAACAGGCCAATAGGACATTATCCTT
TTTGCTGAAATGGATGAGCAGTATGCATTCATTGTTTCCCCTTTATGCAACTGGCTAATTTACT
AACATTCCATGACAAAAAAACAAATGCTCTAAGAAAAAAGGTGTTCAATTGATAAAGAAAAAAA
TATATACATAAAGGTGGATAGATATCCTCACATGACATATATGACATCGCAGCAAGTGCTGCTC
CTCGGTGCATTGCTGTAGAGCATATAGCTGCCTTTTGAAATGACAACTCAAGCAGGGAGCCAGA
TGCGACAATAGCTTCCTGATGATATATGCAATCAACACAGATAACTACTATCAGACTCACTATC
CATATCATGCAGCAGCAATGAACCAAAACACCTTAACATATAAGACACAATAAATTCACCTTTG
GGCAGCAGCGAATAAATGTGGATGTAAAGTTTGCATAGGCTTCAACAAGATCAGGTTCTTGATC
ACATGTGTAAGAAGAATTCAAAGTAGATATTGAAGCTGCAGAGCTAAGTGCTTCGAAAGTTCTG
ACACATAAAGCAACATATTCTTCCTTGTGACCAAATTCTTCAATAACACTGGCAGCTGAAAATG
TCGTTGATGTCAAGGCAGTGTGGAGTCCACAAATATATTGAATAAGATGCTGCAGTAGTATCTT
AGTGTTTTAAGCCTATCTTGTGCATTGTTTTGTAAATGTAAAGCTACAAAATACTTCAAAAATT
ATATTCTAAGAGCATGGGATGGTGGCTAAAAATATATCACAAGTACATAGCAAAGGCAGGTAAA
TAGCAGCTATTGATGTCCCAAATGCTTTAATTAAAGGCAAACCTATGTAGATGGGATTAATCTA
TTCCTGTGAGTACTAGCATATGTATTACTGTGATGTAGGTAGTAATCCACAAGTCAAATGTACA
TGTAAATCAGCAACTGCTAGCATGTTGGTAAAAATACTAGCAAGTTCATTGTAGAGTTGAATAA
CAGAAAGCAAATTACATATGCACACATGTAAACCCTCTTACCTGTTCTTAAGAAGCAGTCATGC
CTTTGAAACAGTAAGAAATTTGTTGATAAGCATTCCAGAACTTTAGGTAACAAAATCTGGAAGT
GTTGTCCTGTAAAATGCAATTGCTTGATCAGCACAACGATCTAATGCTATTAGTCTTGAAATTT
TGCATTGCAGGTATCATTTAACTTACCACAAGAATGTATGGCTGAAGAAAGAGAACGACATGCA
GCTGCAGATAAACTAACATTCTCCATATGAGATGATCGGGAAAGTCTTTCAAGAAGTGGCCAGA
ATATACCAAGAAGAACCAAAACCGTGTCATCATCAATCAGACTAGATGTAATTGATGTCGCCAA
ATGGCCAAATAAAGCACCCATCCTGAAAAAGGAAACTTCATTTTCATTTGCTTACATTGTAGAT
CACAGCATGTTTCTAATTTTCTTCCACGGCATCCAAAAATCCCTCCCAAAATACAATATCCTTA
AAAATAGGTTCAAAATGACTGGTTGTTACTTGTGTTCTTTTATCTGTCAAATTCTATGATCCGG
TCAAAGCATATCATATTGTTTTTTCTATAGCTTGCCATAAATGATCTAAGTGGGAGGATGTAAA
AGTATCCACCTTTCCAAGAACCAAATAACTCCCAACTCAATGGTAAAGCCATCTTTTTATTAAA
GATCACATCAACATCAACCAACAGGAGATGCTTCTCCACTTGCTTTGCTCTCCTTTTGTTAATC
TAGAACAAAGCGGTTTCATGTTTACAGTCAATTTTTCTTCCGCGCAGCTGACTCTAGATAGCAT
TTATTCATCTCTATTGGCTAGAATGTAGTTGGTGATACTGCACAGCTTTCACTGGATAGTTCAA
AAAGTAATATGATTGGATACTTATACATCAATTGAATATATTTATGCTGGCATGTTCTTTTGAT
GATCGCCCCAAAAGCAAATACTCGCTTTCTGCACAACTTTGTACTTCAAGTTGTAGTTATTAGT
TAAGTTATACTTCAATTAAATATCATTCAACATGAGGCTTTGCATAGTTTATGACTTTGAATAG
TCTATAATATGTTGACACAACGGAAAATTGCACCAATATTAATCAAATTTATATTATTTACAGT
ACAAAAAACTATTTTTCTTCAAACTGCTAACTTTAGTACCATTTCGTTAACATGCTTGATTCTT
GAATTAGTCAAGTGTAGTAGTATCATTGAAAAGTGTGGAAGATACAAAAATATATATATTGCTA
GAAAAAATGGGGCCACAAAATGTAAGAATGAAAGAACTTAAAGGCTAAGCACCTGTAGAGACCA
TGGACAGCAAGGTTCAATGCTTCTGTGTAAGCAGCTGGATTTTGCCGCAGAGATTGATCTCTGT
CTATGTCAAT
						
					

			
		

Sequences
Splice junction sequence	TAAAGGCTAAGCACCTGTAGAGACCATGGACAGCAAGGTTCAATGCTTCTGTGTAAGCAGCTGG ATTTTGCCGCAGAGATTGATCTCTGTCTATGTCAATctctgacctcttcgttcccagcttccca aaaaacagaagatgtggagtatgcgacagctaaaccatgtgtttccaagagtatagcatagcaa actccaac
Assembled circRNA sequence	NA The sequence of a circRNA based on assembly using circseq-cup (Ye et al., 2016) or CIRI-full (Zheng and Zhao, 2018) or CIRCexplorer2 (Zhang et al., 2016).
Full-length trsnacripts	NA
Genomic sequence	CTCTGACCTCTTCGTTCCCAGCTTCCCAAAAAACAGAAGATGTGGAGTATGCGACAGCTAAACC ATGTGTTTCCAAGAGTATAGCATAGCAAACTCCAACTTGAGGAACGGTCATTGGCCTCAAGGAT CCTGACCCACTCAAATCTCAGAGCAGCCACTAGTCTGCAGAGTGACCTTGTCCCTTGCAGCCAG GTCTTTTGCATAATAGGCACCAAACGACCTCCTAATCCCGCTAAAAGATAACGGATGGAATATG TGGAGATCAAGCCTTTGGGATCAGCATTGTGACATACCCGTAACGCCAGACAGAAGCTCCACAC GGTCTCTCTTTAGATCCTCATGTGAGCAGTGAGCTCTCCGGGATCATTGACAGCTCCAAAATCA ACACTATTAATCGCGGCAGTTCCATCCGCATGAGGTAGTTTCATCAAACACGTTACGAAGGGCA GGGCATGGGGGCATTCCGATGGCTTTCTGCAAAGTCCCTGACTATACGCTTAAGGGTTCTTCCG CCTTTCCCTTGCATGTAAGCATGGTTGTTTCTGACATTATCACCAGTCCTACTGTGAAGATAGT CTGAGGCTGCATCATGAAGTACGTTGAGCCATAAAGGAACTATCATCTCAGCTTCCCCTTGCCT TAGGTACTCTGAGGGCATAGATTTCACCTGGACAAGATTGGAAAAACGTTAGCCCATGATGGTG TTGCAACACGTCAAAGTTAAGCTTCATGCAGAAAATACATTAGTCGGAAATACTTTTCAAATGA ATATAACACGCCAAAACACCAGAAGGTAGCTCAAAATGTTCAGGTGTCAACAGTACTTGTTACT AGTCCGACATGACAACAATGTCTGCCTACAATCCTACATATATGGATTAATGGCTAGTATGTAG ATGCAAACTGATGATTTCTAGTGACTAAAAATTAGTGTATCATGTAAATCAAATAAACAGAAAT ATCATCTGTAATTTTCAAATGATATTTGACCCAGATCCTCTTGCAAATCCACGTCATGTTCATC GTGATTTTCAAGATTGATGTACAGTACTACTAACCTTATGCATGACATGTGTTCTAATGCTTTG ATGTTAGACGAACAAAAAAATAAACAAAAACACATAGGGTTCCTTTCGCAATTACACCAAGGGG GTTATTGTAGAAATGCAGTACCGCTGATTGCAGCCATCGACAAAGGGAATCCCAAGAAATAATG GCCTTCCACGTTGTTCTCTCACAGAGGCTGCACACTGCTGCCAACTGCTGCAATATTGTTGCAG ATTTATGCACCTGTTGGAAAGAAAGAAATGTGAATATCATGCAAAGTCTCTATGGCCACATATC CTGCCCTCTGAGTGGACCATATTTATAAAAGAATCAAATCATAGATATGATCAATGGTACTAAA CTGGAAAAGCAACAGAAAGTAAACTTTAAGCAAGTAATCATTATGGTCAGGGTGCAAACATAAG CGAGGGAAAAGGTAAAAAGATGGGCTTTGAAGCACAAGCATAGGAGCAATTGTGTGGAAGCAAT GGTACGATGGTGCTCTTTGAAACTGTACCCACCCTTGACAAGGCCGATACACCAAGTAGAGCAT AAAGTACATTTGACATGAGACCTTCACCGCAGCGTGCCAAAATTTGAGCTAGCACCACACCAGG TGATCCATCAGAGGGGTGCTCTCGAGATTCTAGTGCAGCAGCGAGGCTAACATCAAGAAAACCT ACATGTGTCATGGCAAATGATCAAATGAGCACAAAAACATACTAGGTGCTACACGATGTTTCAA GTGCAATAGCTTGAGCTGAATGCTGAAGCATATGTCACAGTAACAGATTAAGGTATGTAAACGG TATGAACAGTGCAGCAAGTACAAATAGATCTTTTAACTCCAAAGGGATTATAAATGTGATGAAA AGAATAACGCTTTCTACCACCAACTCACATTACAGTGATACACTAGTTCCAACAGACATAATAA TGTAACAAACCTTATCCAGAAAGTAGCTGAAAAGGCATCCATGACTTTGCAGGGGAAAAACACT AACTTGACATGATTGCTTACCAGTAGACCACAATCCAAGCATTATTTTTCTTTGCATATACTTT ATCTTCTCAGGGGAATAAATTTCTTTAAATTAAAAAACCAACAGGCCAATAGGACATTATCCTT TTTGCTGAAATGGATGAGCAGTATGCATTCATTGTTTCCCCTTTATGCAACTGGCTAATTTACT AACATTCCATGACAAAAAAACAAATGCTCTAAGAAAAAAGGTGTTCAATTGATAAAGAAAAAAA TATATACATAAAGGTGGATAGATATCCTCACATGACATATATGACATCGCAGCAAGTGCTGCTC CTCGGTGCATTGCTGTAGAGCATATAGCTGCCTTTTGAAATGACAACTCAAGCAGGGAGCCAGA TGCGACAATAGCTTCCTGATGATATATGCAATCAACACAGATAACTACTATCAGACTCACTATC CATATCATGCAGCAGCAATGAACCAAAACACCTTAACATATAAGACACAATAAATTCACCTTTG GGCAGCAGCGAATAAATGTGGATGTAAAGTTTGCATAGGCTTCAACAAGATCAGGTTCTTGATC ACATGTGTAAGAAGAATTCAAAGTAGATATTGAAGCTGCAGAGCTAAGTGCTTCGAAAGTTCTG ACACATAAAGCAACATATTCTTCCTTGTGACCAAATTCTTCAATAACACTGGCAGCTGAAAATG TCGTTGATGTCAAGGCAGTGTGGAGTCCACAAATATATTGAATAAGATGCTGCAGTAGTATCTT AGTGTTTTAAGCCTATCTTGTGCATTGTTTTGTAAATGTAAAGCTACAAAATACTTCAAAAATT ATATTCTAAGAGCATGGGATGGTGGCTAAAAATATATCACAAGTACATAGCAAAGGCAGGTAAA TAGCAGCTATTGATGTCCCAAATGCTTTAATTAAAGGCAAACCTATGTAGATGGGATTAATCTA TTCCTGTGAGTACTAGCATATGTATTACTGTGATGTAGGTAGTAATCCACAAGTCAAATGTACA TGTAAATCAGCAACTGCTAGCATGTTGGTAAAAATACTAGCAAGTTCATTGTAGAGTTGAATAA CAGAAAGCAAATTACATATGCACACATGTAAACCCTCTTACCTGTTCTTAAGAAGCAGTCATGC CTTTGAAACAGTAAGAAATTTGTTGATAAGCATTCCAGAACTTTAGGTAACAAAATCTGGAAGT GTTGTCCTGTAAAATGCAATTGCTTGATCAGCACAACGATCTAATGCTATTAGTCTTGAAATTT TGCATTGCAGGTATCATTTAACTTACCACAAGAATGTATGGCTGAAGAAAGAGAACGACATGCA GCTGCAGATAAACTAACATTCTCCATATGAGATGATCGGGAAAGTCTTTCAAGAAGTGGCCAGA ATATACCAAGAAGAACCAAAACCGTGTCATCATCAATCAGACTAGATGTAATTGATGTCGCCAA ATGGCCAAATAAAGCACCCATCCTGAAAAAGGAAACTTCATTTTCATTTGCTTACATTGTAGAT CACAGCATGTTTCTAATTTTCTTCCACGGCATCCAAAAATCCCTCCCAAAATACAATATCCTTA AAAATAGGTTCAAAATGACTGGTTGTTACTTGTGTTCTTTTATCTGTCAAATTCTATGATCCGG TCAAAGCATATCATATTGTTTTTTCTATAGCTTGCCATAAATGATCTAAGTGGGAGGATGTAAA AGTATCCACCTTTCCAAGAACCAAATAACTCCCAACTCAATGGTAAAGCCATCTTTTTATTAAA GATCACATCAACATCAACCAACAGGAGATGCTTCTCCACTTGCTTTGCTCTCCTTTTGTTAATC TAGAACAAAGCGGTTTCATGTTTACAGTCAATTTTTCTTCCGCGCAGCTGACTCTAGATAGCAT TTATTCATCTCTATTGGCTAGAATGTAGTTGGTGATACTGCACAGCTTTCACTGGATAGTTCAA AAAGTAATATGATTGGATACTTATACATCAATTGAATATATTTATGCTGGCATGTTCTTTTGAT GATCGCCCCAAAAGCAAATACTCGCTTTCTGCACAACTTTGTACTTCAAGTTGTAGTTATTAGT TAAGTTATACTTCAATTAAATATCATTCAACATGAGGCTTTGCATAGTTTATGACTTTGAATAG TCTATAATATGTTGACACAACGGAAAATTGCACCAATATTAATCAAATTTATATTATTTACAGT ACAAAAAACTATTTTTCTTCAAACTGCTAACTTTAGTACCATTTCGTTAACATGCTTGATTCTT GAATTAGTCAAGTGTAGTAGTATCATTGAAAAGTGTGGAAGATACAAAAATATATATATTGCTA GAAAAAATGGGGCCACAAAATGTAAGAATGAAAGAACTTAAAGGCTAAGCACCTGTAGAGACCA TGGACAGCAAGGTTCAATGCTTCTGTGTAAGCAGCTGGATTTTGCCGCAGAGATTGATCTCTGT CTATGTCAAT

			
						 Conservation Information
					
						Conserved circRNAs
						
							NA						
					
						PMCS

Conservation Information
Conserved circRNAs	NA
PMCS

			
						 Functional Information
					
						Coding potential
						N
					
						Potential coding position
						
							NA
						
						Potential amino acid sequence
						
							NA
						
						Sponge-miRNAs
						
							NA						
					
						circRNA-miRNA-mRNA network
						 VISUALIZATION
					
						Potential function description
						NA

Functional Information
Coding potential	N
Potential coding position	NA
Potential amino acid sequence	NA
Sponge-miRNAs	NA
circRNA-miRNA-mRNA network	VISUALIZATION
Potential function description	NA

			
						 Other Information
					
						References
						Huang et al., 2021

circRNA

Detail information of BGIOSGA033849_circ_igg.1

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