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LEC # TOPICS KEY DATES
1 Historical introduction and overview; Gene mapping and network
2

Sequence collection and molecular databases; Sequence alignment and database searching for similar sequences

Introduction/ Dynamic programming algorithm for alignment of pairs of sequence /Dot matrix sequence comparison
3

Sequence alignment and database searching for similar sequences

Assessing the significance of sequence alignments/ Multiple Sequence Alignment /Database Searching for Similar Sequences
4

Genome analysis

Genome composition and structure /Gene Prediction /Comparative genomics/
5

Genetic variation and molecular evolutionary analysis

Introduction /Phylogenetic Prediction /Distance methods /Genetic diversity and evolutionary selection
6 Microarray data and protein structure
7

Utility and realization of bioinformatics tools and databases

To resolve biological questions using local and website bioinformatics tools and databases, including GenBank, InterProt; BLAST, ClustalW, GenDoc, FgeneSH, DNAsp, MEGA,..

Experiment

#1 #2 due

8

References reading, case study and discussion/ Invited speeches

Presentations by selected students and case studies of bioinformatics-related questions.
Experiment #3 #4 due
9 Final Exam